Bioscience Enterprise: Mixing business with science (University of Auckland)

A programme that fuses business and science is showing business-savvy scientists how to commercialise bioscience innovations and create opportunities in the international market.

One of these business-science professionals is Tim McCready, an alumnus of The University of Auckland who now works for New Zealand Trade and Enterprise (NZTE) as a business development consultant.

“I’ve always enjoyed science and seeing the transformative effect it can have on people’s lives. At the same time, a lot of exciting research falls by the wayside because of a lack of business acumen in the industry,” he says.

Deciding to do something about this gap after finishing his Bachelor of Science, McCready joined the inaugural year of the Master of Bioscience Enterprise (MBioEnt) programme in 2006. The bioscience commercialisation degree is taught conjointly by the Business School, the School of Biological Sciences and the Law School.

“I chose a masters degree focused on business because I wanted to have an impact on the innovative science coming from New Zealand, the financial contribution it can give to the New Zealand economy and the difference it makes to lives worldwide,” McCready says.

He did papers on research commercialisation, finance, accounting, marketing, law and intellectual property, followed by a thesis project in the final year.

“I learned that scientists often have little understanding of the steps involved in commercialisation because their interest, understandably, is in research. At the same time, business people with no understanding of science can’t appreciate the length of time, the amount of risk, and the enormous cost involved in commercialising human therapeutics.”

McCready’s comments are echoed by Geoff Whitcher, director of the Business School’s Centre for Entrepreneurial Learning, who believes the MBioEnt is producing scientists with a strong business sense that will be a great help to New Zealand.

“Having an understanding of the science and commercial realities means they can help New Zealand companies to expand their international activities by taking new biotech products into export markets, thus helping New Zealand earn much-needed overseas funds,” Whitcher says.

While working on his thesis, McCready did an internship in the biotechnology team at NZTE. After finishing with first class honours he stayed with the organisation and recently shifted to Investment New Zealand, a division of NZTE focused on attracting investment to New Zealand and helping companies make strategic investments offshore.

This work has taken him to the United States three times in the past year to help New Zealand biotechnology and natural health product companies access the North American market.

Now McCready is working on a project with Living Cell Technologies (LCT), a company that breeds pathogen-free pigs from remote sub-Antarctic islands for its cell-based products to treat insulin-dependent diabetes and neurodegenerative diseases.

The LCT-Investment New Zealand project is looking into global market opportunities for high quality by-products taken from unused pig tissue, which could be used for other medical applications.

“LCT’s pig herds are uniquely free from viruses, bacteria and parasites so they are effectively the cleanest pigs in the world,” says McCready.

“This project is particularly exciting because LCT is one of New Zealand’s premier biotechnology companies making use of the country’s competitive advantage in animal health status.”


Japanese Agriculture, Horticulture & Business

In 2010 I was invited by the Japanese government to visit Tokyo and Hokkaido in an initiative to foster closer connections between New Zealand food producers and businesses. This visit has resulted in continued collaboration between New Zealand and Japan, and taught me a great deal about Japanese business and culture.

Below is an email I sent to colleagues mid-way through my visit to Japan to share what I had learnt.

From: Tim McCready
Sent: Sunday, 11 July 2010 6:21 p.m.

I’ve been slow to write an email to everyone since I arrived in Japan – the Japanese government have done a fantastic job of packing our schedules full of interesting meetings, and I haven’t had a chance until now. Every day we’ve started at around 6, and not back to the hotel until after midnight! Loads of fun though. I’m really loving wandering the main streets with modern skyscrapers, and then turning into an alleyway and seeing the traditional buildings tightly packed together and hidden underground restaurants. A real eclectic mix.

I flew into Sapporo (in Hokkaido, the top part of Japan) today and will be having an early night because we’re going to the fish markets tomorrow at 5am to watch the wholesale tuna bidding. Tokyo has been ridiculously hot and humid, so it’s nice to be in a city now that is still quite warm, but with no humidity at all. There was even a cool breeze tonight, which makes for a nice change!


I visited Asakusa (one of the oldest parts of Japan, and one of the only places packed with souvenir stores) to see one of Japans oldest temples. What our guides didn’t realize was that the day we went (July 10) was the day of 46,000 blessings. Worshiping on that day is apparently equivalent to performing acts of merit for 46,000 days. We weren’t told this until after we left, so, unfortunately, I missed out on 46,000 days worth of merit. I did manage to pick up a few souvenirs but I don’t think I’ve ever seen a crowd like that before.

Part of my programme here allowed me to participate in a formal Japanese tea ceremony. This was particularly interesting because we learnt the rules of the tea ceremony, the kimono they wear during the ceremony, and the art of Japanese flower arranging. It was amazing to see the tradition that is still followed, and how important that still is to people.

We visited an organic farmers market about two hours out of Tokyo. This is an initiative they’ve been using to introduce farming and agriculture to the people of Japan, where people can buy a small allocation of land, and come out from the city a couple of times a month to care for it. While there we got lessons on making some of the fanciest sushi I’ve ever seen in my life (which included sushi shaped into pandas, snails, and flowers). It was ridiculously fiddly and not something you’d be too keen on if you were in a hurry for a meal.

We carried on and visited one of Japans oldest terraced paddy fields. It was interesting to see them up close – the ecosystem at the base of the plant is really interesting (with frogs and tadpoles living in the water). The plants are grown on a bed of clay that has a base of water on top, which is slowly drained down to each paddy field. It was interesting to hear that the farmers with the paddy fields at the top of the hill have the best quality rice because the water is cleanest – but everyone pools their rice together so that the quality remains consistent and there is no difference in the money farmers get for their rice.

On the same day, we visited Japan’s top (2010 gold medal winning) sake brewery in Minnami-no-sato. They also grew their own rice out the back to produce their sake. I never knew you could have so many different varieties of sake – the owner had testing stations (similar to a vineyard), but with over 30 varieties. Some of the sake tasted extremely mild, but some (particularly the 1998 vintage) tasted suspiciously diesel-esque. One of the people in our tour had a bottle of 42 below vodka they had picked up from duty-free on their way to Tokyo, and traded it with the brewery owner for a bottle of sake. The owner picked out his most expensive bottle (over NZ$200 worth) for the exchange – so it worked out a pretty good deal for the kiwis!

The Japanese government is definitely taking good care of us, and taking us to some pretty impressive restaurants. Yesterday we went to a place where sumo wrestlers fight, and had a traditional sumo wrestler (protein rich) Japanese meal. It consisted of your traditional bento box, as well as an enormous bowl of soup cooking on the table that was full of seafood, chicken, plenty of chicken skin, fish, shiitake mushrooms and (one or two) vegetables!

One of the most interesting things I’ve seen here is the fruit and vegetable section at supermarkets. We’ve heard constantly at the talks we’ve been to that Japanese like their food to be safe, healthy, packaged nicely, perfect and consistent – and it’s true. I’ve never seen fruit of the same standard back in New Zealand. People buy individually boxed apples that have absolutely no blemishes on them. The rockmelons are perfectly spherical with the stems left on, which are then trimmed to look exactly the same as all the others.

They have square watermelons here, which are grown inside a container to create the cube shape. The only benefit I can see from this is that it makes them easier to stack in the shop, and they can be wrapped with ribbons and bows to resemble a present. I don’t think this justifies the price – 20,000 yen (about $330 kiwi dollars!), but people seem prepared to pay for it!

I was wondering what they did with fruit that wasn’t perfect. When I asked in meetings I was told that most of it would never be sold – but I did stumble across a seconds bin at one of the supermarkets. They had a bunch of bananas in it – one of the bananas had a single blemish on it – they were far nicer than any bananas I’ve ever seen anywhere else in the world – and they were reduced to clear for $1.50 for the bunch. (No one else in the supermarket seemed interested in buying them so we picked them up and shared them around the delegation!).

Most Japanese produce and meat have little barcodes on them that customers can scan in the store with their mobile phone, and they can instantly see a photo of the farmer, facts about the farm, and how long the farmer has been in business (it comes down to the importance of the safety of food supply again).

We were told that foods labelled as Organic don’t necessarily sell very well in Japan. All Japanese food is of such high quality that consumers assume all products meet that quality, which means there is little differentiation between standard and organic products.

We have had some great meetings with the Ministry of Foreign Affairs and the Ministry of Agriculture, Forestry and Fisheries. The Minster talked to us about a potential Free Trade Agreement with New Zealand, but explained that Japanese farmers are worried that an FTA could threaten their already tight profits. They also feel like New Zealand played its hand when we reduced the tariffs on their car imports into New Zealand, so we have a lot more to gain on an FTA than the Japanese do.

The meeting with the Ministry of Agriculture made it clear that Japan is extremely worried about global warming and greenhouse gas emissions. They are doing a lot to reduce or offset carbon emissions and believe that they are already seeing the effects of global warming on their fruit quality.

The government is also worried about the safety and security of their food supply. Japan produces only 40% of their required food source, and imports the rest from around the world. They are trying really hard to push this up to at least 50%.

Japan does, however, produce almost 100% of its required rice – there are rice paddy fields in every spare piece of land you can imagine. The profits in rice production are ridiculously small, and even though it is a staple of their diet, Japanese people are becoming more westernised and starting to eat alternatives for breakfast. As a result of this, the government is running a huge marketing promotion right now to promote eating rice – they’re even rolling out a lot of new rice products (including rice ice cream and rice pizza) to encourage people to eat it. Some farmers are converting from rice growing to livestock – but because rice paddy fields are mostly located in marginal land this can’t always happen. The rice farmer told us that the farmers in this position can’t even sell their land – no one would want it.

The other big issue facing Japan (as well as the rest of the world) is an ageing population. The population of Japan is ~120 million, but they expect this to almost halve over the next twenty years. Unfortunately, most of their farmers are older people too, because the younger generation isn’t interested in farming and move toward the cities. The Japanese government provide income support to encourage younger farmers into the industry and entice farmers to increase their competitiveness with innovation.

On our visit to the National Institute of Fruit Tree Science (their equivalent of Plant & Food Research in NZ) in Tsukaba city, we got to try a new peach variety that is in development. It was really delicious. Although not as juicy as peaches back at home, it as much sweeter and had more flavor. We also saw some pretty interesting technologies they are experimenting with in the orchid to for nashi pear and apple growing too – they are working hard to produce trees with lower hanging fruit – so that the older generation can continue working and picking fruit well into their 80’s.

Most farms in Japan are run as family farms, and not as an efficient business. We had a 25-year-old farmer from Tokyo come and speak to us at a function in the New Zealand embassy. It was interesting hearing his perspective – he only has 40 cows (on three hectares) and had his whole family of five working full time on the farm. He had spent a bit of time on New Zealand farms with over 1000 cows trying to learn how to improve things. His take on it was that Japan could never compete with New Zealand’s efficient agriculture, so his plans are to add value to his milk by turning it into gelato and setting up a shop near his farm to sell it. A lettuce grower we visited explained that his farm runs at a loss. He works six months of the year away from the family farm in order to provide the money required to run it.

There are 1.28 million more men in Japan than women. Additionally, marriage is happening increasingly later in life, and is even becoming unpopular for women (who often see having kids and a career as mutually exclusive). By 2020 it’s expected that 36% of men in Japan will be single. This means that there are a lot of things sold in supermarkets for individuals (a box with a single apple in it, tiny packages of condiments etc).

One of our speakers told us how Japanese people love new innovative ideas – even if it’s not something life changing but just slightly different. As an example, the supermarkets here roll out a new type of Kit-Kat almost every month and then get rid of it just as quickly. I have seen a yoghurt and aloe vera Kit-Kat, a corn Kit-Kat, and a cantaloupe Kit-Kat – and they sell ridiculously well. Coke seems to be doing the same kind of thing – the coke bottles here at the moment are all shaped like soccer balls (which are challenging to hold) because of the football world cup – and sales have spiked!

Today on our way to the hotel from Sapporo airport, we went past the sites of the 1972 Winter Olympics. We stopped at the ski jump track where we took the gondola to the top and got an amazing view of the city. I also got to stand on the podium and pretend to be an Olympic gold medal winner which is definitely the only time that will happen!

So far Sapporo seems like a really nice city. Because it’s the middle of summer here right now, and Sapporo is the home of Sapporo beer, there are beer gardens and markets set up all over the place. While we’re here we’re visiting a horticulture farmer, a milk production company, the Sapporo brewery, as well as Otaru City (Dunedin’s sister city) to meet with the Otaru Municipal Government.